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10/5/2019 10:16:04 AM
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Bulk Nootropic Oxiracetam Powder Capsule Price
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Bulk Nootropic Oxiracetam Powder Capsule Price
Oxiracetam is a true cognitive enhancer that affects a wide range of cognitive processes, improving everything from attention span to memory, learning capacity,concentration
/focus,sensory perception, and even technical/logical thinking. It also acts as a stimulant, increasing mental energy, alertness, and motivation. Studies show that it is safe and effective in long-term therapy, and there is even clinical evidence that it may even promote and preserve brain health.Nootropics Powder
Oxiracetam is a nootropic drug of the racetam family and stimulant.Several animal studies suggest that the substance is safe even when high doses are consumed for a long period of time. However, the mechanism of action of the racetam drug family is still a matter of research.
Oxiracetam has been studied extensively on both healthy subjects and subjects with mental conditions with much success. There are little to no documented cases of
detrimental effects due to oxiracetam and it is extremely non-toxic and safe for contiuous daily consumption.
Experience does show that taking too much oxiracetam on a single day can result in headaches and possible insomia, however the addition of a choline source usually prevents this. It is advised to regulate any nootropic intake depending on the immediate and longterm effects it produces for an individual.
Oxiracetam is one of the most popular nootropics, well known and highly regarded for its outstanding cognitive enhancement properties and mild stimulant capability. Some of oxiracetam’s benefits include the following:
(1) Improved Memory
Oxiracetam has been shown to improve memory in general, enhancing both memory formation and retention and exerting a significantly positive effect on the speed of recall.
(2) Logical/Technical Thinking Enhancement
While the overwhelming majority of users cite overall learning and memory improvements as major benefits of oxiracetam, a significant percentage of users also report that they experience dramatic improvements in logical and technical thinking ability. Some users also report that oxiracetam improves their analytical and reasoning skills
(3) Learning Enhancement
Virtually all oxiracetam users agree that the supplement makes learning faster and easier, and animal studies have shown this to be true. This effect may be due in part to the greater ease and speed of both memory formation and recall that the supplement creates, but it is also believed to be attributable to an easier and more fluid “thought flow” that most oxiracetam users experience.
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10/5/2019 10:18:23 AM
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Factory Supply Noopept Powder
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Factory Supply Noopept Powder
Nootropics Powder, a strong cognitive enhancer, was developed in Russia in the early 2000s for the treatment of alcohol induced brain damage.
A mind-turning supplement, Noopept is a powerful substance which is able to cross the blood brain barrier. It works primarily by binding to glutamate receptors and exerting strong neuroprotective effects on the brain. Its high bio-availability also means it is fast acting and may have a cumulative effect.
While it is most well known as a brain supplement, Noopept also increases coordination and improves mood. It is able to help fight fatigue and avoid caffeine withdrawals with no noticeable side effects. It makes a great study aid, since it will not cause insomnia.
Some research also indicates that this supplement may help to prevent oxidization damage to the brain. It also works to treat alcohol related brain damage (this was actually the original purpose for its development).
3. Benefits
· Increases coordination
· Improves mood
· Helps fight fatigue
· Prevents oxidation within the brain
· Treats alcohol related brain damage
· Prevents caffeine withdrawal symptoms
4. Scientific Studies
In one of the most well known Russian studies, the effects of noopept supplementation was studied on the rat brain. This included both single and long term (28 days) treatment. Some of the conclusions reached regarding the long term treatment include:
Long term treatment did NOT result in the development of tolerance
The changes caused by the nootropic supplement may play a role in neural restoration
Neurotrophin synthesis in the hippocampus (which the supplement clearly increased) determines cognitive function, especially delayed memory retrieval
Noopept holds much promise to prevent the development of Alzheimer's in patients with mild cognitive impairment
5. Dosage
Suggested dosage is 10-30mg daily.
Volumetric measuring devices cannot be used to accurately measure a supplement powder. Due to the potency and nature of this product, you MUST use a scale with resolution of at least 1 milligram (0.001 grams) which you can find in our store.
6. Synergistic Stacks
Noopept works well in combination with other Nootropic supplements such as Choline CDP, and Vinpocetine.
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10/5/2019 10:20:50 AM
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Pharmaceutical Nootropics Noopept Powder to Enhanc
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Pharmaceutical Nootropics Noopept Powder to Enhance Man′s Cognitive
Noopept powder drugs are described as "Smart Drugs" because, as a whole, this drug category can have an enhancing effect in the areas of memory, focus, cognition, and neurological deficits. The bulk of these drugs have proven to improve conditions like dementia, Alzheimer's disease, and certain types of brain traumas. Noopept is one such nootropic. Noopept is a brand name for a chemical called N-phenylacetyl-L-prolylglycine ethyl ester, which is the synthetic alternative to Piracetam. In order to receive the greatest benefit the required dosage of Noopept is much lower than Piracetam. For example, 4800 mg of piracetam is equated to a daily dosage of Noopept at only 15-30 mg. After administration, Noopept appears to provide a neuro protective effect; however, researchers have yet to explain exactly why this neuro protective element occurs.
Application
Noopept has a similar effect to piracetam, in that it provides a mild cognitive boost after supplementation. Noopept also provides a subtle psychostimulatory effect.
Noopept has a much lower standard dose than piracetam (10-30mg, compared to 4800mg), and it provides a general neuroprotective effect after supplementation. This neuroprotective effect occurs during various states of cognitive trauma, including oxidative stress and physical trauma. There is, however, no evidence to suggest Noopept provides benefits for people with no cognitive ailments.
Noopept Functions
1.Increases coordination
2.Improves mood
3.Helps fight fatigue
4.Prevents oxidation within the brain
5.Treats alcohol related brain damage
6.Prevents caffeine withdrawal symptoms
7 Enhanced nerve growth
NOOPEPT SHORT AND LONG TERM EFFECTS
The short and long-term effects of Noopept use have proven to be beneficial and positive. The increased capacity of memory, attention span, and overall cognition is improved. According to experts, after tests conducted on rabbits, explain that there have been no toxic, allergic, or direct health risks associated with this nootropic
Suggested Use
Noopept is water-soluble, which makes consumption super convenient, it will dissolve uniformly in a glass of water or green tea. Although the most effective way to take it is sub-lingually, meaning that you place it below your tongue and let it dissolve into the floor of your mouth.
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10/5/2019 10:24:00 AM
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Noopept Anti-Alzheimer Powder Gvs-111 Treat Alzhei
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Noopept Anti-Alzheimer Powder Gvs-111 Treat Alzheimer′s Disease
Noopept is not a racetam (due to not having a 2-oxo-pyrrolidine skeleton), but is generally grouped together in the same category because it shares similar mechanisms of action with the racetam family, mainly modulation of the acetylcholine system, as well as modulation of AMPA receptors.
Function
Enhances brain activity, strenthens memory, increase ability to fucus, increase the ability to learn.
It has close ties to the popular racetam family of nootropics that are known for their benefits on cognitive ability as well their neuroprotective properties. What makes Noopept a valuable nootropic in your toolbox is that its effects are felt almost immediately after ingestion.When compared to traditional racetams, it has been found to be, according to studies, 1000 times more potent than the prototypical racetam drug, piracetam.Noopept is a prodrug for the endogenous peptide cycloprolylglycine.As a result, Noopept can be taken in comparably smaller doses to produce the same results as that of Piracetam.
Memory and Learning
Noopept is a nootropic supplement that's been getting a lot of attention lately. Noopept's most emphasized benefit is how it can enhance memory and improve the learning process. Noopept, like Piracetam, assists with memory formation, but with additional benefits not present in the latter, which are memory consolidation and memory retrieval. Noopept facilitates the proper management of all forms of stimuli as they are processed by the brain, which allows for better retrieval of memory. In other words, signals being processed by our senses are more streamlined as they are transported into our brains in the form of memory.
Through the continued use of Noopept, you will notice that you are able to process more information and be able to process them for use in your daily activities. You might even recall names, places, maybe a word spoken in a chance encounter, a song title that you thought you have forgotten before, and so on. Memory lapses will be a thing of the past, or at least kept to a minimum.
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10/5/2019 10:25:49 AM
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20% L-Theanine Green Tea Extract Powder Anti-Radia
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20% L-Theanine Green Tea Extract Powder Anti-Radiation
Product Name
Green Tea Extract 20% L-theanine
General Description
Green Tea Extract 20% L-theanine powder is extracted from the leaf of Camellia sinensis (L.) O. Ktze.. The product is off-white powder and has the function of lowering blood pressure, improving attention and memory and protecting liver and common use as cosmetics, food supplements and medicine.
20% L-Theanine Green Tea Extract Powder Anti-Radiation
Specifications
Physical & Chemical Data:
Appearance: Brown powder
Odour & taste: Characteristic
Loss on drying: 8% max.
Ash: 10% max.
Particle size: 98% pass 80 mesh
Extraction solvent: Purified water
Analytical Quality:
Assay: 20% L-theanine min
Contaminant:
Pb: ≤5ppm
As: ≤1ppm
Cd: ≤1ppm
Hg: ≤1ppm
Total Heavy metals: ≤10ppm
Microbiological:
Total bacterial count: ≤ 1,000cfu/g
Yeast & Moulds: ≤ 100cfu/g
Salmonella: Negative
E-Coli: ≤ 10cfu/g
Standards
Produced under ISO9001 and IP(NON-GMO) System.
Storage
The product may be stored for 24 months in the unopened original container. It shall be stored at ambient temperature, under dry conditions, protected from heat, light and humidity. Powdered material may form dust explosive dust-air mixtures. Low hazard for industrial or commercial handing.
Package:1kg/aluminium foil bag, 25kg/drum (37*37*50cm).
Note:We can customize the packaging according to customer requirements.
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10/5/2019 10:28:02 AM
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Water-Soluble Tea Polyphenol L-Theanine Powder Gre
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Water-Soluble Tea Polyphenol L-Theanine Powder Green Tea Extract Powder L-Theanine
Theanine (L-theanine) is a unique free amino acid in tea, and theanine is glutamic acid γ-ethylamide. Theanine content varies
with the variety and location of tea. Theanine accounts for 1% to 2% of the dry tea. Theanine is a white needle, soluble in water.
With sweet and refreshing taste, is the taste of tea components.
Fuction of L-Theanine Powder/Green Tea Extract
* .L-Theanine will reduce blood pressure,blood sugar,blood lipids.
* .L-Theanine powder with the function of removing radicals and anti-aging;
*.Green tea extract L-theanine can enhance the immune function and prevention of colds;
*.Green tea extract L-theanine will anti-radiation,anti-cancer, inhibiting the increasing of cancer cell;
*.Green tea extract L-theanine powder used to anti-bacterium, with the function of sterilization and deodorization.
5.Application of L-Theanine Powder/Green Tea Extract
1. Applied in food field, boiled eggs with motherwort is a good way to treat dysmenorrhea;
2. Applied in health product field, motherwort honey is a good female health food, which helps to regulate menstruation
nourishing;
3. Applied in pharmaceutical field, motherwort tablets, granules, injection, capsule medicine for the treatment of
gynecological diseases;
4. Applied in cosmetic field, according to legend, Empress Wu on account of eating beauty products which is made
of motherwort
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10/5/2019 10:30:22 AM
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Top Quality API Citicoline Sodium Powder for Nootr
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Top Quality API Citicoline Sodium Powder for Nootropic Supplyment
Product Name: Citicoline Sodium powder
Synonyms: P'-[2-(TRIMETHYLAMMONIO)ETHYL]ESTER CYTIDINE 5'-(TRIHYDROGEN DIPHOSPHATE) INNER SALT MONOSODIUM;cytidine 5'-(trihydrogen diphosphate) p'-[2-(trimethylammonio)ethyl] ester inner salt monosodium salt;CYTIDINE-5'-DIPHOSPHOCHOLINE MONOSODIUM SALT;CYTIDINE-5'-DIPHOSPHOCHOLINE, NA;CYTIDINE-5'-DIPHOSPHOCHOLINE, SODIUM;CYTIDINE 5'-DIPHOSPHOCHOLINE SODIUM SALT;CYTIDINE 5'-DIPHOSPHOCHOLINE SODIUM SALT DIHYDRATE;CITICOLINE SODIUM SALT
CAS: 33818-15-4
MF: C14H25N4NaO11P2
MW: 510.31
EINECS: 251-689-1
Product Categories: Miscellaneous Natural Products;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;API
Mol File: 33818-15-4.mol
Uses Naturally occurring nucleotide; intermediate in the major pathway of lecitin biosynthesis. Neuroprotective. It is used in the treatment of ischemic stroke and head trauma.
Application
The main indications of Citicoline Sodium are acute traumatic brain injury and brain consciousness after the operation. Moreover, Citicoline Sodium can treat central nervous system dysfunction and unconsciousness caused by acute injury, paralysis agitans, tinnitus and nerve deafness, and poisoning caused by sleeping pills. In recent years, Citicoline Sodium is widely used in clinical for treatment of ischemic stroke, cerebral arteriosclerosis, multiinfarct dementia, Alzheimer's disease, and children viral encephalitis.
Function
1. Citicoline Sodium is a brain chemical that occurs naturally in the body.
2. As a medicine, Citicoline is taken by mouth as a supplement or given by IV or as a shot.
3. Citicoline Sodium is used for Alzheimer's disease and other types of dementia, head trauma,cerebrovascular disease such as stroke, age-related memory loss, Parkinson's disease, and glaucoma.
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10/5/2019 10:32:36 AM
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Supply Raw Material Citicoline Sodium Powder with
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Supply Raw Material Citicoline Sodium Powder with High Quality and Reasonable Price
Citicoline Sodium is a complex organic molecule that functions as an intermediate in the biosynthesis of cell membrane phospholipids. Citicoline sodium is also known as CDP-choline and cytidine diphosphate choline (cytidine 5'-diphosphocholine). CDP-choline belongs to the group of biomolecules in living systems known as "nucleotides" that play important roles in cellular metabolism. The basic structure of a nucleotide contains ribose with a nitrogenous base and a phosphate group. CDP-choline is composed of ribose, pyrophosphate, cytosine (a nitrogenous base), and choline.
Citicoline sodium is a nucleoside derivatives which can improve cerebral circulation by means of lowering the resistance of cerebrovascular.It can get into brain tissue through blood-brain barrier and the part of choline that stays in the body is a good donor of methylation which has methylation on much compounds.
What's more,citicoline sodium has a positive effect on promoting recovery and revival of brain function for it can enhance the brainstem ascending reticular activating system,enhance the function of the pyramidal system and improve motor paralysis.
What can Citicoline Sodium do?
The main indications of Citicoline Sodium are acute traumatic brain injury and brain consciousness after the operation. Moreover, Citicoline Sodium can treat central nervous system dysfunction and unconsciousness caused by acute injury, paralysis agitans, tinnitus and nerve deafness, and poisoning caused by sleeping pills. In recent years, Citicoline Sodium is widely used in clinical for treatment of ischemic stroke, cerebral arteriosclerosis, multi infarct dementia, Alzheimer's disease, and children viral encephalitis.Citicoline Sodium is a brain chemical that occurs naturally in the body.As a medicine, Citicoline is taken by mouth as a supplement or given by IV or as a shot.Citicoline Sodium is used for Alzheimer's disease and other types of dementia, head trauma, cerebrovascular disease such as stroke, age-related memory loss, Parkinson's disease, and glaucoma.
Quality Control of Health Sources
1) A system in accordance with GMP standard, supervision on whole production process.
2) Health Sources is equipped with advanced detecting device, such as AFS, GC, HPLC, UV etc, supply the
Detailed Certificate of Analysis.
3) Procurement-Strictly on selecting raw materials.
4) Production-Strictly according to the standard specifications, conform to USP, EP, BP, CP, AJI, FCC etc
Pharmaceutical and/or food standards.
5) Warehousing and storage:Clear and dry condition with suitable temperature.
6) Transportation - Audit and supervise the logistics environment to ensure storage safety.
7) Keep samples for all batches goods to be traceable in case of quality discrepance.
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10/9/2019 6:20:56 AM
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Scott Kay Overcomes Tungsten Carbide Wedding Band
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Scott Kay Overcomes Tungsten Carbide Wedding Band FTC Challenge
After six months of research, The Federal Trade Commission (FTC) completed its investigation of certain advertising claims made by Scott Kay, Inc. and has determined no action is warranted. The National Advertising Division of the Council of Better Business Bureaus (NAD) referred Scott Kay Inc.'s advertising to the Federal Trade Commission after the company declined to participate in a NAD proceeding. The NAD and FTC inquired about Scott Kay Inc.'s claims in advertising, point-of-purchase collateral material and personal demonstrations following a challenge by Frederick Goldman, Inc., a primary supplier of tungsten carbide wedding rings to the jewelry industry. women tungsten rings
The FTC agreed to close its investigation and Scott Kay, Inc. has agreed to ensure that the company will not make expressed or implied claims that tungsten carbide wedding bands are fragile unless the company possesses adequate substantiation for such claims. Nothing in this agreement precludes Scott Kay, Inc. from using the word "brittle" as associated with the hardness factor of Tungsten Carbide as substantiated. Scott Kay, Inc. will refrain from making unsubstantiated claims about the environmental impact of the manufacturing process for BioBlu27 cobalt rings.
"I will continue to demonstrate my strong conviction to the jewelry industry in disclosing the confusion and clarity of the performance of tungsten carbide for use in wedding bands," stated Scott Kay, CEO. "As new contemporary metals are introduced into our industry, especially non-molten metal, such as "cemented carbides" (cemented metals) it is our fiduciary and moral responsibility to test and substantiate all claims, and then release the findings and facts. Fact: Tungsten carbide is brittle. We can't be afraid to admit and represent the truth. Wedding bands should never be at risk of cracking, fracturing or breaking."
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10/9/2019 6:26:08 AM
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The Pros and Cons of Tungsten Wedding Bands
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The Pros and Cons of Tungsten Wedding Bands
Tungsten wedding bands are having a moment. Whether your guy just doesn’t like the look of a traditional gold band, or he has a job that involves some sort of manual labor, it seems that tungsten bands are increasingly becoming more popular with young grooms—and even some brides who want to forego the traditional gold and diamonds.tungsten rings for women in wedding
When you are trying to decide what kind of wedding band to buy before the big day and are considering tungsten, here are a few pros and cons to take into account before swiping that credit card.
Pros of Tungsten Wedding Bands
1. They’re Durable
Tungsten rings are extremely durable, as they are made of a hard, rare metal that is almost virtually indestructible. Tungsten by itself, however, cannot be molded into a ring, so jewelers combine it with carbon atoms to make the piece of jewelry that you’ll place on your spouse’s hand on the day of your ceremony. These rings have a lot of the same qualities as the pure metal, such as a high melting temperature, so if your future spouse tends to be hard on jewelry, a tungsten ring might be a good choice for him or her.
2. They Don’t Scratch
Tungsten wedding rings
Because of the durability of this rare metal, Tungsten rings do not scratch very easily. This is particularly good news for a person who often works with their hands (like a contractor, an EMT, or maybe just someone who types a little too hard on the keyboard). If your spouse is working with tools or is on a sports team with a lot of physical contact, then you can rest assured that the ring will still look as shiny and new as it did on the day of your wedding.
3. They’re Inexpensive
Despite the fact that tungsten is a relatively rare metal, buying one of these wedding bands is much less expensive than many other softer metal rings like gold, silver, or brass. For brides and grooms who are on a budget, this is especially great to know when pricing different ring options. If you are getting married to a person who often misplaces things (or just one who is extremely budget conscious), then this more affordable option might be a better choice for you than a traditional wedding band.
Cons of Tungsten Wedding Bands
1. They Aren’t Malleable
A wedding band is forever, and our bodies unfortunately don’t remain the same throughout a marriage. Whether you lose or gain weight over the years, you can take a gold or silver wedding band to a jeweler and they can re-size it for you fairly easily. With a tungsten ring, however, the metal is not as malleable (due to the toughness of the element) and therefore cannot really be re-sized to fit a changing body. Also, if you are proposing with a tungsten ring and are merely guessing at a size, this could be a risky choice.
2. They Can Get Stuck
In the past few years as tungsten’s popularity has risen, there have been a few stories about these rings getting stuck on someone’s finger without a way to get it off besides a trip to the hospital. Although getting a ring stuck on your finger is probably somewhat of a rare thing, it is definitely something to keep in mind as you’re shopping. Sure, you can save money in the short-term by buying a tungsten ring, but if you have to replace it after cutting it (or paying a very large emergency room bill after a doctor cuts it off for you), is it really worth the savings?
3. They Aren’t Traditional
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10/9/2019 6:28:37 AM
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Why You Shouldn't Buy a Tungsten Wedding Ring
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Why You Shouldn't Buy a Tungsten Wedding Ring
In recent years, tungsten rings have emerged as one of the more popular choices for men’s wedding rings because of their attractive looks, durability and low cost. In fact, tungsten carbide is now the top selling metal for men’s wedding bands in the United States. However, we’re here to tell you that many jewelry stores and producers are not selling tungsten any longer, and the reasons why you should buck the trend and look into other options.brushed mens tungsten rings
The Pros of Tungsten Wedding Rings
First, let’s be clear that there are some reasons to get a tungsten wedding ring.For starters, tungsten carbide is a tough material, and is, in fact, the most scratch resistant material in existence. Tungsten rings are also low cost, especially since you won’t ever need to buff out any scratches.Tungsten has an attractive weight, similar to gold and platinum rings, and will not lose its shape in an accident. This does have the side effect of potentially, causing more injury to your finger, but the ring itself is very resistant to damage.
The Cons of Tungsten Wedding Rings
Despite those merits, we still believe you should not get a tungsten wedding ring, and the cons below serve as our reasons why. Let’s take a look.
Tungsten Rings Cannot Be Resized
It is natural for your fingers to change in size and shape over time. Your knuckles especially will continue to grow long after the rest of our bodies have stopped. However, your tungsten ring is not solderable, meaning the size you get is the size you are stuck with for life. You may even reach a point where you cannot take the ring on or off, which, if it is the latter, could be a real problem… take it from us.Tungsten rings are made in a machine shop (massed produced), not by a jeweler, so while they may be affordable up front, they may cost you later should you need maintenance, a new size, or a replacement.
Meanwhile, gold and platinum rings can be soldered, sized and fixed by most jewelers. You can easily size up your gold or platinum ring in the years to come when you need to make adjustments. But you will have a really difficult time finding anyone who can work on tungsten rings in any capacity and will likely be stuck buying a new one.
Tungsten Can Be Broken
While tungsten is indeed scratch resistant like a diamond, this does not mean that it is indestructible. In its raw form, it’s very brittle and hard to work with. If enough force is applied, a tungsten ring can be broken, shattered, or cut. The rings are not entirely indestructible because pure tungsten rings are not possible. Most rings are around 85% tungsten carbide with the rest being made up of a binding alloy like nickel. If your tungsten ring slips off and falls on a hard surface like granite tile or cement it’s likely the ring will shatter into pieces.We should note that many jewelers will offer lifetime warranties that will provide you with a replacement ring if your ring is accidentally broken. Jewelers will also often offer lifetime sizing policies to give you a replacement ring when the time comes. However, since they are rather inexpensive, the rings themselves have zero intrinsic value and are basically worth 1 penny.
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10/9/2019 6:31:52 AM
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Nootropic Drugs Tianeptine Sodium Salt 30123-17-2
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Nootropic Drugs Tianeptine Sodium Salt 30123-17-2 Steroids Powder
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Heterocycles;Sulfur & Selenium Compounds;Stablon, Coaxil, Tatinol;API;Inhibitors
Melting point : 1800C
Storage temp. : Desiccate at RT
Chemical Properties : White to Yellowish Powder
Usage : Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant
Usage : Tianeptine (INN) (Stablon, Coaxil, Tatinol) is a selective serotonin reuptake enhancer (SSRE) drug used for treating major depressive episodes (mild, moderate, or severe).
Tianeptine Sodium is primarily used for its mood boosting and anti-anxiety properties. This substance also has nootropic abilities in regards to individuals whose cognition is negatively impacted by mood disorders. It has the ability to improve focus and concentration in individuals who have poor attention spans as well.Nootropics Powder
Depressive illness devastates millions of lives. Tianeptine is a neuroprotective antidepressant that reverses the neuronal damage and lasting misery caused by chronic, uncontrolled stress. Tianeptine acts both as a non-sedating anti-anxiety agent and a non-stimulating mood-brightener. Uniquely in clinical medicine, tianeptine acts as a selective serotonin reuptake enhancer. Its puzzling efficacy as an antidepressant illustrates how little modern psychiatric medicine really understands about mind, mood and depression.
Tianeptine is chemically a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Application:
Tianeptine shows efficacy against serious depressive episodes (major depression), comparable to amitriptyline, imipramine and fluoxetine, but with significantly fewer side effects. It was shown to be more effective than maprotiline in a group of people with co-existing depression and anxiety. Tianeptine also displays significant anxiolytic properties and is useful in treating a spectrum of anxiety disorders including panic disorder, as evidenced by a study in which those administered 35% CO2 gas (carbogen) on paroxetine or tianeptine therapy showed equivalent panic-blocking effects. Like many antidepressants (including bupropion, the selective serotonin reuptake inhibitors, the serotonin-norepinephrine reuptake inhibitors, moclobemide and numerous others) it may also have a beneficial effect on cognition in people with depression-induced cognitive dysfunction.
Tianeptine sodium salt is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
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10/9/2019 6:34:39 AM
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Top Quality API Tianeptine Sodium Salt Powder for
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Top Quality API Tianeptine Sodium Salt Powder for Nootropic Supplyment
Tianeptine sodium salt powder has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).
Application
Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5-HT (serotonin; sc-201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake . Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritium-labeled 5-HT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation
Tianeptine is antidepressant. The animal has: the hippocampus pyramidal cells increased spontaneous activity, and accelerating its function was inhibited after recovery; increase in cortical and hippocampal neurons at sites of 5- serotonin reuptake. Tianeptine without following adverse effects: sleep and alertness; cardiovascular system; cholinergic system ( without anticholinergic symptoms ); drug craving.
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10/9/2019 6:37:26 AM
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USA Warehouse Tianeptine Sodium Salt Powder
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USA Warehouse Tianeptine Sodium Salt Powder
Tianeptine has strong antidepressant and anxiolytic properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in elderly patients and in those following alcohol withdrawal; such patients can be more sensitive to the adverse effects of psychotropic drugs. Recent interesting results indicate anticonvulsant and analgesic activity of tianeptine and its possible interaction with adenosine A1 receptors.Tianeptine sodium salt
Tianeptine is neuroprotective via multiple neurochemical and cellular mechanisms. In theory, tianeptine's neuroprotective action makes it a potential life-extension drug. When an organism is under stress, or perceives itself under stress, the hypothalamus secretes corticotropin-releasing hormone/factor (CRH/CRF). CRH/CRF in turn increases secretion of adrenocorticotrophic hormone (ACTH) from the anterior pituitary. ACTH in turn stimulates the release of glucocorticoids from the adrenal cortex. Persistent, uncontrolled physical and psychosocial stress causes excess cortisol secretion from the adrenal glands. Excess cortisol causes dendritic shrinkage in the hippocampus and a contrasting growth of dendrites in the lateral amygdala. These stress-induced changes tend to lower mood; they can cause clinical depression in the genetically vulnerable. Current evidence suggests that tianeptine acts to prevent and even reverse stress-induced neural damage, promoting both neuronal survival and synaptic plasticity.
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10/9/2019 6:40:36 AM
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Female Flibanserin Powder
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Female Flibanserin Powder
Female sex powder flibanserin powder CAS167933-07-5
Flibanserin is the world's first drug to help women with low libido, reducing the libido-suppressing serotonin and increasing the libido-stimulating dopamine.
Functions
This product can directly affect the female brain to control the sexual pleasure area, so as to restore the female gradually declining sexual desire. By modulating the human system that stimulates libido, flibanserin helps restore the balance between inhibition and arousal that leads to healthy sexual expression. The effects of the drug are not immediate; it takes several weeks to get results.Nootropics Powder
Like antidepressants, flibanserin affects the brain's production of chemicals associated with mood and desire. In fact, it was used as a treatment for depression before it became a sex drug.
Flibanserin regulates chemicals in the female brain and only works in women with significantly lower libido. There is no way a drug user can be "aroused" by flibanserin if they are no longer interested in someone. It doesn't overdo it, it's not an aphrodisiac, it just helps balance the chemicals in a woman's brain that make her want to have sex with someone she likes, but not more than normal. But it will take time for the drug to work, and flibanserin needs to be taken daily by women.
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10/9/2019 6:43:20 AM
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Pharmaceutical Raw Powder Flibanserin for Treating
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Pharmaceutical Raw Powder Flibanserin for Treating of Women Hsdd
Flibanserin
CAS:167933-07-5
purity: 99.5%
Molecular formula: C20H21F3N4O
Molecular weight: 390.4
Appearance: White powder
Grade: Pharmaceutical grade
Payment:T/T, Western Union and Money Gram
Delivery:Within 24hours After Your Payment
Express: EMS, DHL, FedEx, etc(door-to-door)
1.A new drug designed to boost sexual desire in women is controversial for some and eagerly awaited by others, but it's hit a potentially serious snag. The drug didn't boost women's desire any more than a placebo in two clinical trials.
2.Flibanserin Hydrochloride powder is a Medical being studied as a non-hormonal treatment for pre-menopausal Female with lacking libido, or a lack of sexual desire. Studies show that about 10-20% of women face hypoactive sexual desire disorder and some say HSDD outnumbers men with sexual problems.Flibanserin is Non-Hormonal, it has no problems associated with other hormonal treatments such as a negative altered mood among other issues.
Product Introduction:
1.November 16, 2009 annual meeting of the European Sexual Medicine Center noted that aftertaking the drug, the number of female sexual life increased by 60%, and the status of their sex life satisfaction. At the same time, they also feel the pressure of their own sex lifeis reduced. The drugs can directly stimulate sexual pleasure area of the brain to adjust toproduce sexual desire in vivo chemical hormone levels.
2.Flibanserin is a novel, non-hormonal drug that has been studied in clinical trials for the treatment of HSDD in premenopausal and postmenopausal women. The application submitted to the FDA is for premenopausal women. Flibanserin is believed to work on key neurotransmitters, or chemicals, in the brain that affect sexual desire.
3.More specifically, it is thought that flibanserin corrects an imbalance of levels of these neurotransmitters by increasing dopamine and norepinephrine (both responsible for sexual excitement) and decreasing serotonin (responsible for sexual inhibition). In clinical studies, flibanserin was evaluated for its ability to increase the frequency of satisfying sexual events, increase the intensity of sexual desire and decrease the associated distress women feel from its loss.
Pharmaceutical Raw Powder Flibanserin for Treating of Women Hsdd 167933-07-5
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10/9/2019 6:46:53 AM
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Hot Selling 99% Flibanserin Powder
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Hot Selling 99% Flibanserin Powder
Flibanserin Hydrochloride,sold under the trade name Addyi, is a medication approved for the treatment of pre-menopausal women with hypoactive sexual desire disorder (HSDD).The medication increases the number of satisfying sexual events per month by about one half to one over placebo from a starting point of about two to three.
Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report that the average number of times they had "satisfying sexual events" rose from 2.8 to 4.5 times a month. However, women receiving placebo reported also an increase of "satisfying sexual events" from 2.7 to 3.7 times a month. Evaluation of the overall improvement of their condition and whether the benefit was meaningful to the women, showed a significantly higher rate of a meaningful benefit in the flibanserin-treated people versus the placebo group.The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.
The effectiveness of flibanserin was evaluated in three phase 3 clinical trials. Each of the three trials had two co-primary endpoints, one for satisfying sexual events (SSEs) and the other for sexual desire. Each of the 3 trials also had a secondary endpoint that measured distress related to sexual desire.
All three trials showed that flibanserin produced a statistically significant increase in the number of SSEs and reduced distress related to sexual desire.
The first two trials used an electronic diary to measure sexual desire, and did not find a statistically significant increase relative to women treated with a placebo. These two trials also measured sexual desire using the Female Sexual Function index (FSFI) as a secondary endpoint, and a statistically significant increase was observed using this latter measure. The FSFI was used as the co-primary endpoint for sexual desire in the third trial, and again showed a statistically significant increase.
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10/9/2019 6:50:30 AM
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Raw Antiinflammatory Antioxidize effect powder Phe
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Raw Antiinflammatory Antioxidize effect powder Phenethyl caffeate
English name: Phenethyl caffeate
Alias: Caffeic acid phenethyl ester (CAPE)
English alias Phenethyl caffeiate; 3,4-Dihydroxy-trans-cinnamic acid phenethyl ester
Product Name: Caffeic acid phenylethyl
CAS No.: 115610-29-2
Molecular Formula: C17H16O4
Molecular Weight: 284.30700
Propolis has a wide range of plant sources, and its chemical composition is extremely complex. So far, more than 20 chemical components have been identified from propolis and more than 300 types, including flavonoids, phenolic acids, decanoic acids, steroids, and amino acids. Classes and other substances. Caffeic acid phenethylester (CAPE) has been identified as one of the main active components in propolis, and many biological activities of propolis are related to CAPE. Therefore, CAPE is a hot topic in the study of active ingredients of foreign propolis in recent years.Phenethyl caffeate
The CAPE structure contains a strong antioxidant catechol structure. Sudina's experiments showed that CAPE can completely block the production of active oxidants in neutrophils at 10 μM, blocking the xanthine oxidase system. Moreover, it was found that propolis containing CAPE has stronger antioxidant activity than CAPE, and CAPE activity is stronger than that of another important component of propolis, galangal, indicating that CAPE is an important component of antioxidant activity. . Ozytlrt et al. studied the antioxidant activity of propolis extracts against acute kidney injury in rats, indicating that the antioxidant effect of propolis extracts is better than VE, and CAPE is one of the main components. The effect of CAPE on lipid peroxides in burned rat serum was found to be that CAPE can reduce SOD consumption by eliminating active oxidizing substances and inhibiting the activity of xanthine oxidase (X0) and NOS, thus playing an antioxidant role. .
Anti-inflammatory effect
Studies have shown that propolis ethanol extract containing CAPE can inhibit carrageenan-induced adjuvant arthritis, pleurisy, and rat paw edema. Extracts that do not contain CAPE have no such activity, suggesting that CAPE is anti-inflammatory. The main component of the effect. In addition, CAPE can inhibit the production of NO. N0 is a free radical produced by iNOS to catalyze the production of L-arginine. Excessive NO can cause damage to the body, and in autoimmune diseases such as rheumatoid arthritis and ulcerative colon. Inflammation and NO synthesis in systemic lupus erythematosus increase. Yun et al. reported that CAPE can inhibit the increase of N0 induced by LPS + IFN-γ, mainly due to the inhibition of iNOS gene by CAPE acting on the NF-kB locus of the iNOS promoter and directly inhibiting the catalytic activity of iNOS activity. Transcription, so CAPE can inhibit the expression of NOS gene and play an anti-inflammatory role. In addition, Michaluart et al. and Mirzoeva et al. reported that CAPE can also inhibit the synthesis of prostaglandin (PG) and leukotrienes. PG is produced by catalysis of arachidonic acid (AA) under COX. There are two isoforms of C0X. It is COX-1 and OX-2, and PG plays an important role in the formation of inflammation. CAPE acts by inhibiting the release of arachidonic acid from the cell membrane and inhibiting the activity of COX-1 and COX-2. Antioxidant effect.
Anti-tumor effect
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10/9/2019 6:52:17 AM
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High Quality Caffeic Acid Phenethyl Ester CAS 1045
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High Quality Caffeic Acid Phenethyl Ester CAS 104594-70-9 Cape
Caffeic acid phenethyl ester (CAPE)/Phenethyl Caffeate is a natural phenolic chemical compound. It is the ester of caffeic acid and phenethyl alcohol.
CAPE is found in a variety of plants. It is also a component of propolis from honeybee hives.Phenethyl caffeate powder
Function
1. Caffeic acid phenethyl ester has been shown to inhibit carcinogenesis, although other experiments show possible carcinogenic effects. It is also known as an antioxidant in vitro and also in vivo.
2. Caffeic acid phenethyl ester also shows immunomodulatory and anti-inflammatory activity.
3. Caffeic acid phenethyl ester outperformed the other antioxidants, reducing aflatoxin production by more than 95 percent. The studies are the first to show that oxidative stress that would otherwise trigger or enhance.Aspergillus flavus aflatoxin production can be stymied by caffeic acid. This opens the door to using natural anti-fungicide methods by supplementing trees with antioxidants.
4. Caffeic acid phenethyl ester outperformed the other antioxidants, reducing aflatoxin production by more than 95 percent. The studies are the first to show that oxidative stress that would otherwise trigger or enhance. Aspergillus flavus aflatoxin production can be stymied by caffeic acid. This opens the door to using natural anti- fungicide methods by supplementing trees with antioxidants.
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10/9/2019 6:54:52 AM
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High Purity Pharmaceutical Raw Material Cetilistat
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High Purity Pharmaceutical Raw Material Cetilistat White Crystalline Powder for Sale
Cetilistat (also known as ATL-962) was approved in September 2013 by the Japanese Ministry of Health, Labor and Welfare for the treatment of obesity, limited to patients with both type 2 diabetes mellitus (T2DM) and dyslipidemia, and with a body mass index (BMI)25 kg/m2 in spite of dietary treatment and/or exercise therapy. As with orlistat, cetilistat works via inhibition of pancreatic lipases in the gut to inhibit fat absorption and thereby reduce caloric uptake from diet. The medicinal chemistry program has not been described in the scientific literature, but the patent describing cetilistat also describes the synthesis of analogs with varied aryl substituents and lipophilic tails. The synthesis of cetilistat involves condensation of a hexadecylcarbonochloridate with 2-amino-5-methylbenzoic acid; other analogs were synthesized by varying the carbonochloridate and 2-aminobenzoic acid components. Cetilistat is a potent inhibitor of human and rat pancreatic lipase with IC50s of 15 and 136 nM, respectively, with little inhibition of trypsin or chymotrypsin.
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